The future technologies of drug delivery systems Essay

The future technologies of drug delivery systems - Essay Example teins or synthetic gene design have matured to the level where they can transferred to industrial applications in recombinant protein design (Kayser & Warzecha, 2012). On the basis on genetic code, numerous proteins that have been approved for clinical use are subjected to alterations. These changes occur in amino acid substitution so as to improve the pharmacokinetic and pharmacodynamic activity. In addition, these changes also lead to the development of antagonist functionality. These derived proteins with site directed mutations are referred to as muteins and display good pharmacological attributes. Several approved recombinant therapeutic products are engineered post-biosynthesis. From the molecular biology background, post-translational engineering is associated with glycosylation or lipidation post-biosynthesis (Kayser & Warzecha, 2012). A drug delivery system (DDS) is defined as a formulation or device that allows the introduction of a therapeutic substance in the body, such a system is capable of improving the efficacy as well as safety of the substance by controlling the rate, time and place of release of the drug in the body. This process includes the administration of the therapeutic product, the release of active ingredients across the biological membrane to the site of action (Jain, 2008). The majority of the pharmacological attributes of classic drugs can be enhanced by the use of drug delivery systems. These include particulate carriers mostly comprising of polymers and lipids as well as their associated therapeutics. Drug delivery systems are devised to change the biodistribution and pharmacokinetics of the drugs. Alternatively, these drug delivery systems function as reservoirs for the associated drugs (Allen & Cullis, 2004). The main objective of medicine and pharmacy is the delivery of any medication at the right time in a safe and reproducible fashion to a particular target and at the appropriate level. However, this requirement is often